An Unsettled Debate About the Potential Role of Infection in Pathogenesis of Atherosclerosis

Abstract

Association of infection with atherosclerosis is by no means new. Several sero-epidemiological and pathologic studies as well as animal models have shown a link between infection and atherosclerosis. Exciting discoveries in recent times related to role of inter-individual genetic variation in modulating inflammatory response to infection have reignited the enthusiasm in proving a causal link between infection and atherosclerosis. The purpose of this article was to review and analyze the available evidence linking infection with atherosclerosis.




J Clin Med Res. 2017;9(7):547-554
doi: https://doi.org/10.14740/jocmr3032w