Impact of the Absolute Difference in Diastolic Blood Pressure Between Arms in Patients With Coronary Artery Disease

Yuka Hitaka, Shin-ichiro Miura, Rie Koyoshi, Yuhei Shiga, Yuiko Miyase, Kenji Norimatsu, Ayumi Nakamura, Sen Adachi, Takashi Kuwano, Makoto Sugihara, Amane Ike, Hiroaki Nishikawa, Keijiro Saku


Background: We investigated the relationship between the severity and presence of coronary artery disease (CAD) and a difference in systolic and diastolic blood pressure (SBP and DBP) between arms or between lower limbs.

Methods: We enrolled 277 patients who underwent coronary angiography. We calculated the absolute (|right BP (rt. BP) - left BP (lt. BP)|) and relative (rt. BP - lt. BP) differences in SBP or DBP between arms or between lower limbs, and assessed the severity of CAD in terms of the Gensini score.

Results: The absolute difference in DBP between arms in the CAD group was significantly lower than that in the non-CAD group, whereas the absolute difference in DBP between lower limbs in the CAD group was significantly higher. There were no differences in the absolute or relative difference in SBP between arms or lower limbs between the groups. The absolute difference in DBP between arms decreased as the Gensini score increased. In a logistic regression analysis, the presence of CAD was independently associated with the absolute difference in DBP between arms, in addition to male, family history, dyslipidemia, diabetes mellitus and hypertension.

Conclusion: The absolute difference in DBP between arms in addition to traditional factors may be a critical risk factor for the presence of CAD.

J Clin Med Res. 2015;7(11):873-879


Diastolic blood pressure; Coronary artery disease; Difference in blood pressure between arms; Traditional risk factors

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