J Clin Med Res

Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access

Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc

Journal website https://www.jocmr.org

Short Communication

Volume 14, Number 11, November 2022, pages 487-491

Alterations in Laboratory Parameters Related to Disease Severity in Vaccinated Patients Against SARS-CoV-2

Figure

Figure 1. Statistically significant difference of LDH and PaO₂/FiO₂ ratio in adults with COVID-19. The box plots show the data from all patients analyzed. In every box plot, the upper line is the highest measurement detected. All measurements are grouped as vaccinated (1) and unvaccinated (2) patients. COVID-19: coronavirus disease 2019; LDH: lactate dehydrogenase; PO₂/FiO₂: arterial oxygen partial pressure/fractional inspired oxygen.

Table

**Table 1.** Epidemiological Data, Laboratory Findings and Outcome of the Two Groups of Patients
	COVID-19 vaccinated	COVID-19 unvaccinated	P value
	Group A	Group B	P value
COVID-19: coronavirus disease 2019; M: male; F: female; WBC: white blood cell; CRP: C-reactive protein; LDH: lactate dehydrogenase; PO₂/FiO₂: arterial oxygen partial pressure/fractional inspired oxygen.
Gender
M/F, n	17/4	35/20	0.317
Age (years)	74 ± 13	62 ± 14.7	0.031
WBC (× 10³/µL)	8,168.95 ± 7,584.4	8,521.9 ± 6,571.3	0.848
Lymphocytes (× 10³/µL)	3,052.1 ± 7,230.7	1,218.6.1 ± 167.4	0.087
Monocytes (× 10³/µL)	672.6 ± 384.7	637.9 ± 477.8	0.754
D-dimers	1,348.5 ± 1,397.6	1,850.9 ± 3,877.5	0.575
LDH (U/L)	274.2 ± 85.6	387.5 ± 223.4	0.003
Ferritin (mg/dL)	1,082.8 ± 1,399.5	1,327.4 ± 1,307.8	0.508
CRP (mg/dL)	6.92 ± 4.9	7.4 ± 5.9	0.732
PO₂/FiO₂	355.6 ± 129.7	260.5 ± 123.3	0.006
High-sensitive troponin	113.6 ± 318.1	157.5 ± 48.8	0.252
Outcome (survive/death), n	17/4 (19%)	40/15 (27.3%)	0.310