Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc
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Volume 13, Number 9, September 2021, pages 466-473

Inflammatory Bowel Disease and Patients With Mental Disorders: What Do We Know?


Figure 1.
Figure 1. Inflammatory bowel disease-associated pathogenetic mechanisms of mental disorders. CD: Crohn’s disease; PD: Parkinson’s disease; IBD: inflammatory bowel disease; ASD: autism spectrum disorder.


Table 1. Mental Disorders Associated With Inflammatory Bowel Disease
Psychiatric diseases
  Depression [7]
  Bipolar disorder [8, 9]
  Schizophrenia [10]
  Alzheimer’s disease [14, 15]
  Parkinson’s disease [16]
  Vascular dementia [20, 21]
Autism spectrum disorders [11-13]
Genetic syndromes
  Down syndrome [17]
  Turner syndrome [18]
  Williams syndrome [19]


Table 2. Management of Patients With Inflammatory Bowel Disease and Mental Disorder
Collaboration between gastroenterologists, neurologists, psychiatrists and patient’s family members
Deep sedation during endoscopy
Subcutaneous biological agents might be preferred due to better compliance
Avoid corticosteroid treatment
Second-generation corticosteroids could be preferred
Physical activity
Avoid alcohol and narcotics use