Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc
Journal website https://www.jocmr.org

Original Article

Volume 13, Number 7, July 2021, pages 377-386


Association Between Obesity and Cancer Mortality: An Internal Medicine Outpatient Clinic Perspective

Figures

Figure 1.
Figure 1. Frequencies of types of cancers.
Figure 2.
Figure 2. Frequencies of patients in each BMI category. BMI: body mass index.

Tables

Table 1. Baseline Characteristics
 
VariableCancer non-survivors (N = 43)Cancer survivors (N = 741)P
SD: standard deviation; HTN: hypertension; CAD: coronary artery disease; CVA: cerebrovascular accident; PAD: peripheral artery disease; CAS: carotid artery stenosis; CHF: congestive heart failure; BMI: body mass index; HbA1c: glycosylated hemoglobin.
Age, mean (SD)78.7 (11.8)68.0 (13.5)< 0.001
Gender
  Male (n, %)23 (53)265 (35.8)0.019
  Female (n, %)20 (46)476 (64.2)
Race
  White (n, %)33 (76.7)509 (68.7)0.606
  Black (n, %)4 (9.3)63 (8.5)
  Hispanic (n, %)1 (2.3)29 (3.9)
  Other (n, %)5 (11.6)140 (18.9)
Social factors
  Cigarettes (n, %)23 (53.5)303 (40.9)0.103
  Alcohol (n, %)21 (48.0)426 (57.5)0.265
Cancer type
  Breast cancer (n, %)5 (11.6)181 (24.4)0.152
  Colorectal cancer (n, %)4 (9.3)42 (5.7)
  Prostate cancer (n, %)6 (14.0)98 (13.2)
  Gynecological cancer (n, %)1 (2.3)55 (7.4)
  Other cancer (n, %)27 (62.8)365 (49.3)
Comorbidities
  HTN (n, %)32 (74.4)442 (59.8)0.650
  Diabetes mellitus (n, %)18 (41.9)152 (20.6)0.015
  Hyperlipidemia (n, %)29 (67.4)432 (58.3)0.236
  Hypothyroidism (n, %)10 (23.3)151 (20.4)0.650
  CAD (n, %)12 (27.9)106 (14.3)0.015
  CVA (n, %)6 (14.0)36 (4.9)0.023
  PAD (n, %)10 (23.3)31 (4.2)< 0.001
  CAS (n, %)1 (2.3)23 (3.1)1.000
  CHF (n, %)9 (20.9)41 (5.5)0.001
  Arthritis (n, %)15 (34.9)199 (26.9)0.251
  Rheumatologic disease (n, %)5 (11.6)60 (8.1)0.391
  Depression (n, %)8 (18.6)121 (16.3)0.696
  Anxiety (n, %)10 (23.3)158 (21.3)0.794
Family history
  Breast cancer (n, %)6 (14.0)205 (27.7)0.051
  Colorectal cancer (n, %)2 (4.7)130 (17.5)0.028
  Prostate cancer (n, %)2 (4.7)78 (10.5)0.802
  Gynecological cancer (n, %)2 (4.7)66 (8.9)0.573
  Other cancer (n, %)16 (37.2)303 (40.9)0.633
Other parameters
  BMI, mean (SD)25.0 (5.0)28.1 (6.4)0.008
  HbA1c, mean (SD)7.1 (2.4)6.0 (0.9)< 0.001

 

Table 2. Influence of Risk Factors on Cancer Mortality
 
Risk factorBPExp(B)95% CI for Exp(B)
LowerUpper
CI: confidence interval; HbA1c: glycosylated hemoglobin; CRC: colorectal cancer; DM: diabetes mellitus; CAD: coronary artery disease; CVA: cerebrovascular accident; CHF: congestive heart failure; PAD: peripheral artery disease.
Age (years)0.0730.0011.0761.0301.124
Gender0.2750.5521.3170.5323.256
Non-obese1.5870.0084.8891.51115.810
HbA1c0.4660.0061.5941.1402.230
Family history of CRC0.8010.3072.2280.47810.375
DM0.1950.7111.2150.4343.402
CAD0.0890.8621.0930.4022.973
CVA0.5610.3971.7530.4796.417
CHF0.6010.5792.6510.8927.866
PAD1.2470.0233.4801.18810.190