Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access |
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc |
Journal website https://www.jocmr.org |
Original Article
Volume 13, Number 7, July 2021, pages 377-386
Association Between Obesity and Cancer Mortality: An Internal Medicine Outpatient Clinic Perspective
Figures
Tables
Variable | Cancer non-survivors (N = 43) | Cancer survivors (N = 741) | P |
---|---|---|---|
SD: standard deviation; HTN: hypertension; CAD: coronary artery disease; CVA: cerebrovascular accident; PAD: peripheral artery disease; CAS: carotid artery stenosis; CHF: congestive heart failure; BMI: body mass index; HbA1c: glycosylated hemoglobin. | |||
Age, mean (SD) | 78.7 (11.8) | 68.0 (13.5) | < 0.001 |
Gender | |||
Male (n, %) | 23 (53) | 265 (35.8) | 0.019 |
Female (n, %) | 20 (46) | 476 (64.2) | |
Race | |||
White (n, %) | 33 (76.7) | 509 (68.7) | 0.606 |
Black (n, %) | 4 (9.3) | 63 (8.5) | |
Hispanic (n, %) | 1 (2.3) | 29 (3.9) | |
Other (n, %) | 5 (11.6) | 140 (18.9) | |
Social factors | |||
Cigarettes (n, %) | 23 (53.5) | 303 (40.9) | 0.103 |
Alcohol (n, %) | 21 (48.0) | 426 (57.5) | 0.265 |
Cancer type | |||
Breast cancer (n, %) | 5 (11.6) | 181 (24.4) | 0.152 |
Colorectal cancer (n, %) | 4 (9.3) | 42 (5.7) | |
Prostate cancer (n, %) | 6 (14.0) | 98 (13.2) | |
Gynecological cancer (n, %) | 1 (2.3) | 55 (7.4) | |
Other cancer (n, %) | 27 (62.8) | 365 (49.3) | |
Comorbidities | |||
HTN (n, %) | 32 (74.4) | 442 (59.8) | 0.650 |
Diabetes mellitus (n, %) | 18 (41.9) | 152 (20.6) | 0.015 |
Hyperlipidemia (n, %) | 29 (67.4) | 432 (58.3) | 0.236 |
Hypothyroidism (n, %) | 10 (23.3) | 151 (20.4) | 0.650 |
CAD (n, %) | 12 (27.9) | 106 (14.3) | 0.015 |
CVA (n, %) | 6 (14.0) | 36 (4.9) | 0.023 |
PAD (n, %) | 10 (23.3) | 31 (4.2) | < 0.001 |
CAS (n, %) | 1 (2.3) | 23 (3.1) | 1.000 |
CHF (n, %) | 9 (20.9) | 41 (5.5) | 0.001 |
Arthritis (n, %) | 15 (34.9) | 199 (26.9) | 0.251 |
Rheumatologic disease (n, %) | 5 (11.6) | 60 (8.1) | 0.391 |
Depression (n, %) | 8 (18.6) | 121 (16.3) | 0.696 |
Anxiety (n, %) | 10 (23.3) | 158 (21.3) | 0.794 |
Family history | |||
Breast cancer (n, %) | 6 (14.0) | 205 (27.7) | 0.051 |
Colorectal cancer (n, %) | 2 (4.7) | 130 (17.5) | 0.028 |
Prostate cancer (n, %) | 2 (4.7) | 78 (10.5) | 0.802 |
Gynecological cancer (n, %) | 2 (4.7) | 66 (8.9) | 0.573 |
Other cancer (n, %) | 16 (37.2) | 303 (40.9) | 0.633 |
Other parameters | |||
BMI, mean (SD) | 25.0 (5.0) | 28.1 (6.4) | 0.008 |
HbA1c, mean (SD) | 7.1 (2.4) | 6.0 (0.9) | < 0.001 |
Risk factor | B | P | Exp(B) | 95% CI for Exp(B) | |
---|---|---|---|---|---|
Lower | Upper | ||||
CI: confidence interval; HbA1c: glycosylated hemoglobin; CRC: colorectal cancer; DM: diabetes mellitus; CAD: coronary artery disease; CVA: cerebrovascular accident; CHF: congestive heart failure; PAD: peripheral artery disease. | |||||
Age (years) | 0.073 | 0.001 | 1.076 | 1.030 | 1.124 |
Gender | 0.275 | 0.552 | 1.317 | 0.532 | 3.256 |
Non-obese | 1.587 | 0.008 | 4.889 | 1.511 | 15.810 |
HbA1c | 0.466 | 0.006 | 1.594 | 1.140 | 2.230 |
Family history of CRC | 0.801 | 0.307 | 2.228 | 0.478 | 10.375 |
DM | 0.195 | 0.711 | 1.215 | 0.434 | 3.402 |
CAD | 0.089 | 0.862 | 1.093 | 0.402 | 2.973 |
CVA | 0.561 | 0.397 | 1.753 | 0.479 | 6.417 |
CHF | 0.601 | 0.579 | 2.651 | 0.892 | 7.866 |
PAD | 1.247 | 0.023 | 3.480 | 1.188 | 10.190 |