Figure 1. Diagram of the search strategy.
| Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc |
| Journal website https://www.jocmr.org |
Original Article
Volume 12, Number 11, November 2020, pages 740-746
Retroperitoneoscopic Standard or Hand-Assisted Versus Laparoscopic Standard or Hand-Assisted Donor Nephrectomy: A Systematic Review and the First Network Meta-Analysis
Figures
Tables
| Author, year, country | Study | Number of patients, RPDN/LDN | Age, RPDN/LDN | BMI, RPDN/LDN | NOS (max = 9) |
|---|---|---|---|---|---|
| RPDN: retroperitoneoscopic donor nephrectomy; LDN: laparoscopic donor nephrectomy; BMI: body mass index; HALDN: hand-assisted laparoscopic donor nephrectomy; HARDN: hand-assisted retroperitoneoscopic donor nephrectomy; MD: mean difference; HQ: high quality; NOS: Newcastle-Ottawa scale. | |||||
| Buell et al, 2004 [14], USA | RPDN-HALDN | 28/31 | 44.5 ± 8.5/41.1 ± 11.5 | 26 ± 3.8/26.8 ± 4.4 | 7 |
| Sundqvist et al, 2004 [13], Sweden | HARDN-LDN | 11/14 | 48 ± 6.75/53.5 ± 7.25 | 26 ± 2.5/25.7 ± 1.75 | 7 |
| Bachmann et al, 2006 [15], Switzerland | RDN-HALDN | 77/47 | 54 ± 13/48 ± 5 | 26/24 | 7 |
| Ruszat et al, 2006 [16], Switzerland | RDN-LDN | 65/14 | 53 ± 10/46 ± 10 | 26 ± 4/24 ± 3 | 7 |
| Ruszat et al, 2006 [16], Switzerland | RDN-HALDN | 65/34 | 53 ± 10/50 ± 13 | 26 ± 4/24 ± 3 | 7 |
| Troppmann et al, 2009 [17], USA | HARDN-HALDN | 45/45 | 47 ± 10.75/45 ± 11 | 26.3 ± 3.78/26.6 ± 3.45 | 8 |
| Dols et al, 2013 [18], the Netherlands | HARDN-LDN | 95/95 | 52.8 ± 11.8/52.4 ± 11.7 | 26 ± 3.5/26.2 ± 3.5 | 9 |
| Klop et al, 2013, [19], the Netherlands | HARDN-LDN | 82/86 | 54 ± 11/52 ± 11.5 | NR | 8 |
| Pooled estimates (total 769) | 403 (53%)/366 (47%) | MD = 2.27 (-0.10, 4.65) | MD = 0.81 (-0.26, 1.87) | HQ = 8 | |
| Outcome of interests | Number of studies, and patients (%; events/total) | Statistical method, estimated effect, 95% CIs | P value | I2 (%) |
|---|---|---|---|---|
| MD: mean difference; OR: odds ratio; RE: random-effects; FE: fixed-effects; CIs: confidence intervals; WIT: warm ischemic time; EBL: estimated blood loss; HLOS: hospital length of stay; BMI: body mass index. | ||||
| Age [13-19] | 8, 834 | MD = 2.27 (-0.10 to 4.65) | 0.06 | 59 |
| Gender (male) [13-19] | 8, 834 (40; 187/468) (51; 186/366) | OR = 0.77 (0.44 to 1.34) | 0.35 | 65 |
| BMI [13-18] | 7, 666 | MD = 0.81 (-0.26 to 1.87) | 0.14 | 82 |
| Right kidney retrieval [15-17] | 4, 392 (25; 62/252) (4; 6/140) | OR = 5.43 (1.10 to 26.76) | 0.04 | 60 |
| Renal arteries > 1 [14, 17-19] | 4, 507 (24; 59/250) (22; 56/257) | OR = 1.10 (0.73 to 1.68) | 0.65 | 0 |
| Conversion to open [14, 16, 17] | 4, 427 (2.4; 6/253) (3.4; 6/174) | OR = 0.54 (0.17 to 1.73) | 0.30 | 0 |
| Operative time (min) [13-17] | 8, 834 | MD = -36.96 (-54.68 to -19.25) | 0.001 | 92 |
| EBL (mL) [13, 14, 16-18] | 6, 542 | MD = -39.60 (-84.08 to 4.88) | 0.08 | 77 |
| WIT (s) [13-18] | 7, 666 | MD = -47.88 (-97.74 to 1.99) | 0.06 | 95 |
| Intraoperative complications [14, 16-18] | 5, 517 (7; 20/298) (10; 21/219) | Peto OR = 0.66 (0.34. 1.29) | 0.29 | 43 |
| Postoperative graft complications [14, 16-18] | 5, 626 (13; 44/352) (9; 25/274) | OR = 1.05 (0.61, 1.30) | 0.85 | 25 |
| HLOS [13-19] | 7, 710 | MD = 0.09 (-0.07 to 0.24) | 0.28 | 24 |
| Day 1 postoperative pain [15, 18] | 2, 314 | MD = -0.57 ((-1.75 to 0.60) | 0.34 | 91 |
| Day 2 postoperative pain [15, 18] | 2, 314 | MD = 0.09 (-0.27 to 0.46) | 0.62 | 12 |
| Day 3 postoperative pain [15, 18] | 2, 314 | MD = -0.23 (-0.53 to 0.06) | 0.12 | 0 |