Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access |
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Letter to the Editor
Volume 12, Number 8, August 2020, pages 539-541
Are Patients With Autoimmune Disease at Greater Risk of Developing Severe COVID-19?
Table
Inpatients with comorbid autoimmune disease (n = 7) | Inpatients without comorbid autoimmune disease (n = 14) | Normal range of parameters compared | P value | |
---|---|---|---|---|
COVID-19: coronavirus disease 2019; SD: standard deviation; WBC: white blood cell; TNF: tumor necrosis factor; IL: interleukin. | ||||
Sex (male/female), % | 0/100 | 14.3/85.7 | - | 0.481 |
Age, years (mean ± SD) | 57 ± 21 | 64.6 ± 6.8 | - | - |
Immune-modulatory therapies | Yes: interferon α, anti-TNF-α, anti-IL-6 | No | - | - |
Duration of hospitalization, days (mean ± SD) | 7.14 ± 2.6 | 8 ± 3.1 | - | 0.771 |
Serum ferritin (mean ± SD) | 442 ± 200 | 319.7 ± 88 | 12 - 300 mg/dL (male); 12 - 150 mg/dL (female) | 0.800 |
Plasma D-dimers (mean ± SD) | 762.5 ± 104.2 | 1,090 ± 1,131.4 | < 500 µg/dL | 0.667 |
Lactate dehydrogenase (mean ± SD) | 307.5 ± 92.3 | 277.7 ± 55.07 | 120 - 220 U/L | 0.945 |
Plasma fibrinogen (mean ± SD) | 424.5 ± 104 | 624 ± 135.6 | 200 - 400 mg/dL | 0.114 |
Lymphocyte count (mean ± SD) | 1,806.5 ± 897.6 | 1,242.1 ± 355.8 | 20-50% of WBC, k/µL | 0.445 |
Mortality (n) | 0 | 0 | - |