Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access |
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc |
Journal website http://www.jocmr.org |
Original Article
Volume 11, Number 9, September 2019, pages 635-641
Change in the Antimicrobial Resistance Profile of Extended-Spectrum β-Lactamase-Producing Escherichia coli
Figures
Table
Number of antibioticsa | Pattern ID | Antibiotics | Non-ESBL (n = 983) | ESBL (n = 320) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cephamycin | Oxacephem | Carbapenems | Aminoglycosides | Tetracycline | Fluoroquinolones | n | % | n | % | |||||
AMK: amikacin; CMZ: cefmetazole; CPFX: ciprofloxacin; ESBL: extended-spectrum beta-lactamase; ESBL-EC: ESBL-producing Escherichia coli; FMOX: flomoxef; GM: gentamicin; IPM: imipenem; LVFX: levofloxacin; MEPM: meropenem; MINO: minocycline. aThe number of antibiotics to which Escherichia coli isolates were resistant. | ||||||||||||||
0 | Null | 670 | 68.2 | 24 | 7.5 | |||||||||
Subtotal | 670 | 68.2 | 24 | 7.5 | ||||||||||
1 | I-a | CMZ | 5 | 0.5 | 0 | 0.0 | ||||||||
I-b | MEPM | 1 | 0.1 | 0 | 0.0 | |||||||||
I-c | AMK | 1 | 0.1 | 0 | 0.0 | |||||||||
I-d | GM | 22 | 2.2 | 11 | 3.4 | |||||||||
I-e | MINO | 34 | 3.5 | 0 | 0.0 | |||||||||
I-f | CPFX | 5 | 0.5 | 0 | 0.0 | |||||||||
Subtotal | 68 | 6.9 | 11 | 3.4 | ||||||||||
2 | II-a | CMZ | FMOX | 1 | 0.1 | 1 | 0.3 | |||||||
II-b | CMZ | GM | 2 | 0.2 | 0 | 0.0 | ||||||||
II-c | CMZ | MINO | 0 | 0.0 | 1 | 0.3 | ||||||||
II-d | GM | MINO | 5 | 0.5 | 2 | 0.6 | ||||||||
II-e | GM | CPFX | 2 | 0.2 | 1 | 0.3 | ||||||||
II-f | MINO | CPFX | 2 | 0.2 | 0 | 0.0 | ||||||||
II-g | MINO | LVFX | 1 | 0.1 | 0 | 0.0 | ||||||||
II-h | CPFX | LVFX | 131 | 13.3 | 183 | 57.2 | ||||||||
Subtotal | 144 | 14.6 | 188 | 58.8 | ||||||||||
3 | III-a | CMZ | FMOX | GM | 1 | 0.1 | 0 | 0.0 | ||||||
III-b | CMZ | FMOX | LVFX | 0 | 0.0 | 1 | 0.3 | |||||||
III-c | CMZ | CPFX | LVFX | 3 | 0.3 | 1 | 0.3 | |||||||
III-d | FMOX | IPM | MEPM | 1 | 0.1 | 0 | 0.0 | |||||||
III-e | IPM | CPFX | LVFX | 1 | 0.1 | 0 | 0.0 | |||||||
III-f | AMK | CPFX | LVFX | 1 | 0.1 | 0 | 0.0 | |||||||
III-g | GM | MINO | LVFX | 1 | 0.1 | 0 | 0.0 | |||||||
III-h | GM | CPFX | LVFX | 55 | 5.6 | 35 | 10.9 | |||||||
III-i | MINO | CPFX | LVFX | 23 | 2.3 | 47 | 14.7 | |||||||
Subtotal | 86 | 8.7 | 85 | 26.6 | ||||||||||
4 | IV-a | CMZ | FMOX | CPFX | LVFX | 1 | 0.1 | 0 | 0.0 | |||||
IV-b | CMZ | GM | CPFX | LVFX | 2 | 0.2 | 1 | 0.3 | ||||||
IV-c | CMZ | MINO | CPFX | LVFX | 1 | 0.1 | 2 | 0.6 | ||||||
IV-d | IPM | MINO | CPFX | LVFX | 1 | 0.1 | 0 | 0.0 | ||||||
IV-e | AMK | MINO | CPFX | LVFX | 0 | 0.0 | 1 | 0.3 | ||||||
IV-f | GM | MINO | CPFX | LVFX | 5 | 0.5 | 6 | 1.9 | ||||||
Subtotal | 10 | 1.0 | 10 | 3.1 | ||||||||||
5 | V-a | CMZ | FMOX | GM | CPFX | LVFX | 2 | 0.2 | 0 | 0.0 | ||||
V-b | CMZ | FMOX | MINO | CPFX | LVFX | 2 | 0.2 | 2 | 0.6 | |||||
V-c | CMZ | GM | MINO | CPFX | LVFX | 1 | 0.1 | 0 | 0.0 | |||||
Subtotal | 5 | 0.5 | 2 | 0.6 | ||||||||||
7 | VII | CMZ | FMOX | IPM | MEPM | GM | CPFX | LVFX | 0 | 0.0 | 1 | 0.3 | ||
Subtotal | 0 | 0.0 | 1 | 0.3 |