Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc
Journal website http://www.jocmr.org

Original Article

Volume 11, Number 9, September 2019, pages 635-641


Change in the Antimicrobial Resistance Profile of Extended-Spectrum β-Lactamase-Producing Escherichia coli

Figures

Figure 1.
Figure 1. Samples analyzed in the present study.
Figure 2.
Figure 2. Yearly rate of detection of ESBL-EC among all the E. coli isolates.
Figure 3.
Figure 3. Antimicrobial resistance profiles of non-ESBL-EC and ESBL-EC (**P < 0.01).
Figure 4.
Figure 4. Trends in the rates of resistance of ESBL-EC for GM, MINO, CPFX, and LVFX (*P < 0.05).
Figure 5.
Figure 5. Changes in the antimicrobial resistance patterns of non-ESBL-EC and ESBL-EC.

Table

Table 1. Antimicrobial Resistance Pattern of Non-Extended-Spectrum β-Lactamase-Producing Escherichia coli and Extended-Spectrum β-Lactamase-Producing Escherichia coli
 
Number of antibioticsaPattern IDAntibioticsNon-ESBL (n = 983)ESBL (n = 320)
CephamycinOxacephemCarbapenemsAminoglycosidesTetracyclineFluoroquinolonesn%n%
AMK: amikacin; CMZ: cefmetazole; CPFX: ciprofloxacin; ESBL: extended-spectrum beta-lactamase; ESBL-EC: ESBL-producing Escherichia coli; FMOX: flomoxef; GM: gentamicin; IPM: imipenem; LVFX: levofloxacin; MEPM: meropenem; MINO: minocycline. aThe number of antibiotics to which Escherichia coli isolates were resistant.
0Null67068.2247.5
Subtotal67068.2247.5
1I-aCMZ50.500.0
I-bMEPM10.100.0
I-cAMK10.100.0
I-dGM222.2113.4
I-eMINO343.500.0
I-fCPFX50.500.0
Subtotal686.9113.4
2II-aCMZFMOX10.110.3
II-bCMZGM20.200.0
II-cCMZMINO00.010.3
II-dGMMINO50.520.6
II-eGMCPFX20.210.3
II-fMINOCPFX20.200.0
II-gMINOLVFX10.100.0
II-hCPFXLVFX13113.318357.2
Subtotal14414.618858.8
3III-aCMZFMOXGM10.100.0
III-bCMZFMOXLVFX00.010.3
III-cCMZCPFXLVFX30.310.3
III-dFMOXIPMMEPM10.100.0
III-eIPMCPFXLVFX10.100.0
III-fAMKCPFXLVFX10.100.0
III-gGMMINOLVFX10.100.0
III-hGMCPFXLVFX555.63510.9
III-iMINOCPFXLVFX232.34714.7
Subtotal868.78526.6
4IV-aCMZFMOXCPFXLVFX10.100.0
IV-bCMZGMCPFXLVFX20.210.3
IV-cCMZMINOCPFXLVFX10.120.6
IV-dIPMMINOCPFXLVFX10.100.0
IV-eAMKMINOCPFXLVFX00.010.3
IV-fGMMINOCPFXLVFX50.561.9
Subtotal101.0103.1
5V-aCMZFMOXGMCPFXLVFX20.200.0
V-bCMZFMOXMINOCPFXLVFX20.220.6
V-cCMZGMMINOCPFXLVFX10.100.0
Subtotal50.520.6
7VIICMZFMOXIPMMEPMGMCPFXLVFX00.010.3
Subtotal00.010.3