Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc
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Volume 11, Number 7, July 2019, pages 465-471

Updates in Treatment of Recurrent Clostridium difficile Infection


Table 1. RCTs Comparing FMT With Pharmacotherapy
AuthorSample (n)InterventionComparisonOutcome in the FMT groupFollow-up period
RCT: randomized controlled trial; FMT: fecal microbiota transplantation; V: vancomycin; F: fidaxomicin; C: colonoscopy; E: enema; NJ: nasojejunal; ND: nasoduodenal.
Van Nood et al 2013 [38]42FMT via ND tube preceded by V for 4 days and bowel lavageV for 14 days and V for 14 days followed by bowel lavageResolution of symptoms in 15/16 (94%) patients5 weeks
G Cammarota et al 2015 [12]39V for 3 days followed by FMT via CV for 10 days followed by every 2-3 days for 3 weeksResolution of symptoms in 18/20 (90%) patients10 weeks
Susy S. Hota et al 2017 [13]30V for 14 days followed by FMT via E6-week taper of VResolution of symptoms in 7/16 (43.8%) patients120 days
Hvas et al 2019 [39]64V for 4 - 10 days followed by FMT via C or NJ tubeV for 10 days, F for 10 daysClinical resolution and negative CD test in 17/24 (71%)8 weeks