Figure 1. Light microscopy of kidney biopsy specimen (stained with H&E) showed tubulointerstitial inflammation: interstitial inflammatory infiltrates with prominent granular sites including eosinophils and neutrophils.
| Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc |
| Journal website http://www.jocmr.org |
Case Report
Volume 10, Number 10, October 2018, pages 791-794
Dabigatran-Induced Acute Interstitial Nephritis: An Important Complication of Newer Oral Anticoagulation Agents
Figures
Table
| Laboratory examinations | Baseline | 4 weeks after initiation of dabigatran | At admission | 1 week after corticosteroid therapy |
|---|---|---|---|---|
| Table shows the laboratory values before and 4 weeks after initiation of dabigatran, prior to hospitalization, and 1 week after initiation of corticosteroid therapy. | ||||
| Biochemistry (normal values) | ||||
| Sodium (136 - 145 mmol/L) | 144 | 143 | 135 | 143 |
| Potassium (3.5 - 5.2 mmol/L) | 3.9 | 4.5 | 4.2 | 4.3 |
| Chloride (96 - 110 mmol/L) | 112 | 114 | 118 | 114 |
| Bicarbonate (24 - 31 mmol/L) | 20 | 11 | 12 | 22 |
| Blood urea nitrogen (5 - 25 mg/dL) | 35 | 103 | 115 | 53 |
| Creatinine (0.61 - 1.24 mg/dL) | 1.3 | 4.7 | 5.06 | 2.73 |
| Glucose (70 - 99 mg/dL) | 101 | 96 | 121 | 195 |
| International normalized ratio (0.88 - 1.15) | 2.3 | 3.9 | 4.01 | 2.1 |
| Complete blood count | ||||
| White cell count (4.5 - 11.0 ku/L) | 9.5 | 17.8 | 19.2 | 17.5 |
| Hemoglobin (12.0 - 17.5 g/dL) | 11.1 | 8.9 | 8.0 | 8.6 |
| Hematocrit (36 - 53) | 34 | 27 | 23.1 | 27.1 |
| Platelets (140 - 450 ku/L) | 277 | 381 | 426 | 454 |