| Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc |
| Journal website http://www.jocmr.org |
Original Article
Volume 11, Number 1, January 2019, pages 1-6
Risk Factors Associated With Recurrent Clostridium difficile Infection
Tables
| Variable | Frequency | Recurrence | P value |
|---|---|---|---|
| Age (mean (standard deviation)) | 59 (18.0) | ||
| Sex | 0.058 | ||
| Female (n, %) | 266 (61.3) | 67 (25.1) | |
| Male (n, %) | 168 (38.7) | 29 (17.3) | |
| Race | 0.840 | ||
| Caucasian (n, %) | 217 (63.5) | 50 (14.6) | |
| African American (n, %) | 68 (19.9) | 17 (5.0) | |
| Hispanic (n, %) | 44 (12.9) | 9 (2.6) | |
| Asian (n, %) | 5 (1.5) | 1 (0.3) | |
| Other (n, %) | 8 (2.3) | 3 (0.9) | |
| Setting | 0.555 | ||
| Inpatient (n, %) | 263 (60.6) | 61 (23.2) | |
| Outpatient (n, %) | 171 (39.4) | 35 (20.5) |
| Variable | Frequency (n, %) | Recurrence (n, %) | P value |
|---|---|---|---|
| *Indicates statistical significance. Meds: medications. | |||
| Inpatients | 1.000 | ||
| ICU | 34 (7.8) | 7 (20.6) | |
| Non-ICU medical unit | 400 (92.2) | 89 (22.3) | |
| Method of nutrition | 0.228 | ||
| Artificial tube feeds | 26 (6.0) | 3 (11.5) | |
| Non-tube feeds | 409 (94.0) | 93 (22.7) | |
| Ventilation | 1.000 | ||
| Mechanical ventilation | 11 (2.5) | 2 (18.2) | |
| Non-mechanical ventilation | 424 (97.5) | 94 (22.2) | |
| Severity | 0.260 | ||
| Mild/moderate | 338 (78.4) | 71 (21.0) | |
| Severe | 93 (21.6) | 25 (26.9) | |
| Treatment | 0.919 | ||
| Metronidazole | 216 (51.2) | 47 (21.8) | |
| Vancomycin | 152 (36.0) | 34 (22.4) | |
| Combination | 54 (12.8) | 13 (24.1) | |
| Antisecretory use | 1.000 | ||
| On antisecretory Meds | 221 (51.8) | 50 (22.6) | |
| Not on antisecretory Meds | 206 (48.2) | 46 (22.3) | |
| Prior antibiotic use | 0.727 | ||
| On antibiotics | 191 (43.9) | 44 (23.0) | |
| Not on antibiotics | 244 (56.1) | 52 (21.3) | |
| Chemotherapy Use | 1.000 | ||
| On chemotherapy | 57 (13.1) | 12 (21.1) | |
| Not on chemotherapy | 378 (86.9) | 84 (22.2) | |
| Stool softener use | 0.359 | ||
| On stool softeners | 53 (15.2) | 8 (15.1) | |
| Not on stool softeners | 296 (84.8) | 65 (22.0) | |
| Presence of colectomy | 0.014* | ||
| Prior partial colectomy | 22 (5.1) | 10 (45.5) | |
| No prior partial colectomy | 413 (94.9) | 86 (20.8) | |