Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc
Journal website http://www.jocmr.org

Original Article

Volume 10, Number 4, April 2018, pages 345-350

The Relationship Between Mean Platelet Volume and Fasting Plasma Glucose and HbA1c Levels in a Large Cohort of Unselected Health Check-Up Participants

Figures

Figure 1.
Figure 1. Study flow diagram.
Figure 2.
Figure 2. Pearson’s correlation showing a linear relation between mean platelet volume (MPV) and fasting plasma glucose (FPG).
Figure 3.
Figure 3. Pearson’s correlation showing a linear relation between mean platelet volume (MPV) and HbA1c.
Figure 4.
Figure 4. Distribution of mean platelet volume (MPV) in groups stratified according to the HbA1c values. Box-whisker plots of MPV in each group categorized by HbA1c value: group 1 (HbA1c < 5.5%), group 2 (5.5% ≤ HbA1c < 5.9%), group 3 (6.0% ≤ HbA1c < 6.5%), and group 4 (HbA1c ≥ 6.5%), are presented. Lines indicate interquartile range.

Tables

Table 1. Characteristic of the Entire Subjects (n = 38,204)
 
Characteristics
FPG: fasting plasma glucose; MPV: mean platelet volume.
Age, mean (SD), years52.3 (12.1)
Male, n (%)17,622 (46.1)
FPG, mean (SD), mg/dL98.9 (11.3)
HbA1c, mean (SD), %5.5 (0.4)
MPV, mean (SD), fL9.97 (0.71)

 

Table 2. Characteristics and Laboratory Data of the Subjects Categorized According to HbA1c Value
 
Group 1Group 2Group 3Group 4P value
MPV: mean platelet volume; FPG: fasting plasma glucose.
HbA1c (%)< 5.55.5 - 5.96.0 - 6.4≥ 6.5
Number of subjects15,97418,0443,529657
Male, number (%)6,957 (43.6)8,452 (46.8)1,760 (49.9)453 (68.9)< 0.001
Age, mean (SD), years47 (11)54 (12)61 (11)62 (12)< 0.001
MPV, mean (SD), fL9.96 (0.71)9.97 (0.71)9.99 (0.70)10.09 (0.72)< 0.001
Platelets, mean (SD), 109/L216 (43.5)217 (45.1)218 (47.8)214 (46.4)0.007
FPG, mean (SD), mg/dL95.0 (7.5)99.2 (8.4)108.3 (11.4)136.2 (33.4)< 0.001