J Clin Med Res

Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access

Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc

Journal website http://www.jocmr.org

Review

Volume 9, Number 11, November 2017, pages 891-899

C-Reactive Protein as an Independent Cardiovascular Risk Predictor in HIV+ Patients: A Focused Review of Published Studies

Figure

Figure 1. Flow diagram demonstrating step-wise application of inclusion and exclusion criteria to arrive at included articles.

Table

**Table 1.** Association of CVE, CRP and Other Risk Factors
Study	Total cohort	Study design	Prior CVD	Major conventional risk factors	Lipid lowering drug use	HIV-related risk factors			ART-related risk factors			CRP and CVE association
Study	Total cohort	Study design	Prior CVD	Major conventional risk factors	Lipid lowering drug use	Prior AIDS	HIV duration	Viral load/CD4 count	Treated or naive	Duration	Regimen	CRP and CVE association
CS: case; CN: control; CVE: cardiovascular event; RC: retrospective cohort; RS: retrospective study; PS: prospective study; +CRP: elevated CRP; -CRP: CRP normal; PR: association present; ADJ: association adjusted for confounders; ABS: association absent; NA: not applicable; NR: not reported; NC: not controlled.
Triant, 2009 [36]	487	RC	NR	Some NR	ABS	NR	NR	ABS	NA	NR	PR, ADJ	PR
	287 CS (+CRP)								All treated
	200 CN (-CRP)
Duprez et al, 2012 [37]	5,098	PS	PR, ADJ	PR, ADJ	NC	PR, ADJ	NC	ABS	ADJ	NC	NC	PR
	252 CVE+			Some NR
	4,846 CVE-
De Luca et al, 2013 [38]	109	RS	NR	PR, ADJ	ADJ	ABS	ABS	ABS	ABS	PR, ADJ	PR, ADJ	PR
	35 CS (CVE+)			Some NR
	74 CN (CVE-)
Ford et al, 2010 [40]	156	RS	NR	PR, ADJ	ABS	NR	ABS	ABS	NA	ABS	ABS	ABS
	52 CS (CVE+)			Some NR					All treated
	104 CN (CVE-)
Westhorpe et al, 2014 [39]	99	RS	NR	Some NR	NC	NC	NC	ABS	ABS	NC	ABS	ABS
	33 CS (CVE+)
	66 CN (CVE-)