Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc
Journal website http://www.jocmr.org

Short Communication

Volume 9, Number 9, September 2017, pages 809-811

The Apelin Receptor APJ in Hematopoietic Stem Cells/Progenitor Cells in the Early Stage of Non-Alcoholic Steatohepatitis

Figures

Figure 1.
Figure 1. Immunohistochemical expression of APJ. (a, b) In normal control liver, APJ shows positive staining at vascular regions and capillaries in the periportal area. (c, d) In early-stage NASH liver, APJ shows strong positive staining at hepatic sinusoidal lining cells and inflammatory cells in the pericentral area and positive staining at hepatic sinusoidal lining cells in the periportal area. P: portal tract; c: central vein; BD: bile duct. (a, c) Low magnification. (b, d) High magnification.
Figure 2.
Figure 2. Immunoelectron microscopic observation of APJ in early NASH liver. (a) APJ expression is aberrantly observed at the proliferated arterial capillaries opening into the sinusoid. (b) APJ expression is localized at proliferated capillary ECs and pericytes. (c) APJ expression is localized at HSCs/HPCs. S: hepatic sinusoid; EC: endothelial cell; H: hepatocyte; p: pericyte; HSC/HPC: hematopoietic stem cell/progenitor cell. (a) Low magnification. (b, c) High magnification.