Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access |
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc |
Journal website http://www.jocmr.org |
Original Article
Volume 9, Number 12, December 2017, pages 994-997
A Comparison of the Effects and Side Effects of Oral Betahistine with Injectable Promethazine in the Treatment of Acute Peripheral Vertigo in Emergency
Tables
Variables | Group A (n = 82) | Group B (n = 80) | P value |
---|---|---|---|
Age (range) | 43.5 (19 - 64) | 40.1 (17 - 66) | NS |
Gender | |||
Female | 45 (54.9%) | 42 (52.5%) | NS |
Male | 37 (45.1%) | 38 (47.5%) | NS |
Variable | Time | Group A (n = 82) | Group B (n = 80) | P value |
---|---|---|---|---|
VAS: visual analog scale. | ||||
VAS (mean ± SD) | Before intervention | 6.26 ± 1.22 | 6.44 ± 0.6 | NS |
1 h | 5.09 ± 1.39 | 4.84 ± 1.14 | NS | |
2 h | 4.28 ± 1.3 | 3.38 ± 0.98 | 0.043 | |
3 h | 3.39 ± 1.3 | 2.7 ± 0.75 | 0.039 | |
Vertigo after intervention (h) | 1.7 ± 0.59 | 1.6 ± 0.39 | NS |
Time | Clinical symptoms | Group A (n = 82) | Group B (n = 80) | P value |
---|---|---|---|---|
Before intervention | Tinnitus | 76 (92.7%) | 79 (98.8%) | NS |
Nausea and vomiting | 6 (7.3%) | 1 (1.3%) | ||
1 h | Tinnitus | 7 (8.5%) | 5 (6.3%) | 0.0298 |
Nausea and vomiting | 39 (47.6%) | 52 (65%) | ||
Drowsiness | 17 (20.7%) | 0 | ||
None | 19 (23.2%) | 23 (28.8%) | ||
2 h | Tinnitus | 1 (1.2%) | 5 (6.3%) | 0.0412 |
Nausea and vomiting | 11 (13.4%) | 28 (35%) | ||
Drowsiness | 54 (65.9%) | 0 | ||
Cardiac arrhythmia | 0 | 1 (1.3%) | ||
None | 16 (19.5%) | 46 (57.5%) | ||
3 h | Tinnitus | 1 (1.2%) | 3 (3.8%) | 0.0398 |
Nausea and vomiting | 3 (3.7%) | 11 (13.8%) | ||
Drowsiness | 51 (62.2%) | 0 | ||
Cardiac arrhythmia | 0 | 1 (1.3%) | ||
None | 27 (32.9%) | 65 (81.3%) |
Adverse effect | Group A (n = 82) | Group B (n = 80) | P value |
---|---|---|---|
Restlessness | 11 (13.4%) | 0 | 0.038 |
Anxiety | 2 (2.4%) | 0 | |
Drowsiness | 63 (76.8%) | 0 | |
None | 6 (7.3%) | 80 (100%) |