J Clin Med Res

Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access

Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc

Journal website http://www.jocmr.org

Original Article

Volume 9, Number 5, May 2017, pages 433-438

Traumatic Abdominal Solid Organ Injury Patients Might Benefit From Thromboelastography-Guided Blood Component Therapy

**Table 1.** Comparisons Between TEG Versus Non-TEG-Guided Blood Component Transfusion Among Liver and Spleen Injury Patients
Traumatic liver/spleen injury	TEG-guided (N = 86)	Non-TEG-guided (N = 80)
SD: standard deviation; N: number; ED: emergency department; SBP: systolic blood pressure; GCS: Glasgow coma scale; ISS: injury severity scale; PRBC: packed red blood cell; FFP: fresh frozen plasma; TEG: thromboelastography; ICU: intensive care unit. ^ϮOthers in race: include Asian, Pacific Islander, Hispanic, or unknown. *P < 0.01; P < 0.05. ^¶Study excluded patients who died within the first 24 h of hospital arrival.
Patient characteristics
Age (years), mean (SD)**	34 (14)	42 (19)
Gender male (%)	70	65
Race (%)
Caucasian	71	71
African American	22	22
Others^Ϯ	7	6
Clinical variables
Type of injury blunt (%)	81	81
ED SBP (mm Hg), mean (SD)*	118 (26)	107 (34)
ED hear rate (bpm), mean (SD)	103 (20)	102 (23)
ED respiratory rate, mean (SD)	19 (5)	19 (6)
ED GCS, mean (SD)	11 (5)	10 (5)
Initial abnormal TEG (%) (n)	53 (46)	45 (36)
ISS, mean (SD)*	28 (13)	32 (13)
ISS, mean (SD)^¶	28 (13)	31 (13)
Blood transfusion
PRBC unit, mean (SD)**	4 (7)	9 (10)
FFP unit, mean (SD)**	1 (5)	5 (6)
Platelet unit, mean (SD)**	0.4 (1.5)	2.9 (4.8)
Cryoprecipitate unit, mean (SD)	0.1 (0.5)	0.3 (1.2)
Outcome measurements
In-hospital total mortality (%) (n)	12 (10)	19 (15)
In-hospital 24-h mortality (%) (n)	3 (3)	10 (8)
In-hospital post 24-h mortality (%) (n)^¶	8.1 (7)	8.8 (7)
Hospital total length of stay (days), mean (SD)	14 (12)	18 (16)
Hospital total length of stay (days), mean (SD)^¶*	14 (12)	19 (16)
Total ICU length of stay (days), mean (SD)*	8.5 (10.5)	12.3 (13.8)
Total ICU length of stay (days), mean (SD)^¶*	8.8 (10.6)	13.6 (14.0)

Table 1. Comparisons Between TEG Versus Non-TEG-Guided Blood Component Transfusion Among Liver and Spleen Injury Patients

Traumatic liver/spleen injury

TEG-guided (N = 86)

Non-TEG-guided (N = 80)

SD: standard deviation; N: number; ED: emergency department; SBP: systolic blood pressure; GCS: Glasgow coma scale; ISS: injury severity scale; PRBC: packed red blood cell; FFP: fresh frozen plasma; TEG: thromboelastography; ICU: intensive care unit. ^ϮOthers in race: include Asian, Pacific Islander, Hispanic, or unknown. **P < 0.01; *P < 0.05. ^¶Study excluded patients who died within the first 24 h of hospital arrival.

Patient characteristics

Age (years), mean (SD)**

34 (14)

42 (19)

Gender male (%)

Race (%)

Caucasian

African American

Others^Ϯ

Clinical variables

Type of injury blunt (%)

ED SBP (mm Hg), mean (SD)*

118 (26)

107 (34)

ED hear rate (bpm), mean (SD)

103 (20)

102 (23)

ED respiratory rate, mean (SD)

19 (5)

19 (6)

ED GCS, mean (SD)

11 (5)

10 (5)

Initial abnormal TEG (%) (n)

53 (46)

45 (36)

ISS, mean (SD)*

28 (13)

32 (13)

ISS, mean (SD)^¶

28 (13)

31 (13)

Blood transfusion

PRBC unit, mean (SD)**

4 (7)

9 (10)

FFP unit, mean (SD)**

1 (5)

5 (6)

Platelet unit, mean (SD)**

0.4 (1.5)

2.9 (4.8)

Cryoprecipitate unit, mean (SD)

0.1 (0.5)

0.3 (1.2)

Outcome measurements

In-hospital total mortality (%) (n)

12 (10)

19 (15)

In-hospital 24-h mortality (%) (n)

3 (3)

10 (8)

In-hospital post 24-h mortality (%) (n)^¶

8.1 (7)

8.8 (7)

Hospital total length of stay (days), mean (SD)

14 (12)

18 (16)

Hospital total length of stay (days), mean (SD)^¶*

14 (12)

19 (16)

Total ICU length of stay (days), mean (SD)*

8.5 (10.5)

12.3 (13.8)

Total ICU length of stay (days), mean (SD)^¶*

8.8 (10.6)

13.6 (14.0)

**Table 2.** Factors Associated With Hospital Length of Stay Using Multivariate Linear Regression Analysis^¶
Factors	Coefficiency	95% confidence interval	P value	VIF
Ramsey RESET: P = 0.09. ED: emergency department; SBP: systolic bood pressure; GCS: Glasgow coma scale; ISS: injury severity scale; TEG: thromboelastography; VIF: variance inflation factor; RESET: regression equation specification error test. ^¶Study excluded patients who died within the first 24 h of hospital arrival.
Age	-0.11	-0.25 to 0.04	0.14	1.14
Initial ED SBP	-0.06	-0.14 to 0.02	0.16	1.12
Initial ED GCS	-0.30	-0.77 to 0.16	0.20	1.18
Initial abnormal TEG results	-1.85	-6.44 to 2.75	0.43	1.07
Injury severity scale (ISS)	0.03	-0.16 to 0.23	0.74	1.27
Non-TEG-guided BCT	5.44	0.69 to 10.18	0.03	1.13

Table 2. Factors Associated With Hospital Length of Stay Using Multivariate Linear Regression Analysis^¶

Factors

Coefficiency

95% confidence interval

P value

VIF

Ramsey RESET: P = 0.09. ED: emergency department; SBP: systolic bood pressure; GCS: Glasgow coma scale; ISS: injury severity scale; TEG: thromboelastography; VIF: variance inflation factor; RESET: regression equation specification error test. ^¶Study excluded patients who died within the first 24 h of hospital arrival.

Age

-0.11

-0.25 to 0.04

0.14

1.14

Initial ED SBP

-0.06

-0.14 to 0.02

0.16

1.12

Initial ED GCS

-0.30

-0.77 to 0.16

0.20

1.18

Initial abnormal TEG results

-1.85

-6.44 to 2.75

0.43

1.07

Injury severity scale (ISS)

0.03

-0.16 to 0.23

0.74

1.27

Non-TEG-guided BCT

5.44

0.69 to 10.18

0.03

1.13