Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc
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Case Report

Volume 8, Number 11, November 2016, pages 824-830

Primary B-Cell Mucosa-Associated Lymphoid Tissue Lymphoma of the Hard Palate and Parotid Gland: Report of One Case and Review of the Literature

Figures

Figure 1.
Figure 1. Clinical features of the patient at admission. (a) Swelling of the right parotid gland. (b) A 2 × 2.5 cm mass with central ulceration on the right hard palate.
Figure 2.
Figure 2. Findings on cervical MRI. (a) Isointense mass lesion on the hard palate on sagittal, T1-weighted plane. (b) Mass lesion on the right side of the hard palate on coronal, T1-weighted, fat-saturated, contrast-enhanced sequence. (c) Mass lesion in the right parotid gland on axial, T1-weighted, contrast-enhanced plane.
Figure 3.
Figure 3. Histopathological findings of the palatal mass. (a) Subepithelial infiltration of atypical centrocyte-like cells with or without clear cytoplasm (H&E stain, × 400). (b) Infiltrated cells in the hard palate with CD20 expression (H&E stain, × 400).
Figure 4.
Figure 4. Case image and clinical findings after six cycles of chemotherapy. (a) Total regression of the ulcerated mass on the right hard palate. (b) Disappearance of the mass at the right palatal region on T1-weighted coronal MRI.

Table

Table 1. Clinical Features of MALT Lymphoma With Hard Palate Involvement
 
CaseRef.Age/sexAutoimmune diseaseSize (mm)LocationPalatal ulcerationTreatmentResponseOutcomeFU
A: alive; CR: complete remission; DOD: died of disease; FU: follow-up; NR: not recorded; RD: relapsed disease; R: rituximab; Ref.: references; RT: radiation therapy; SS: Sjogren’s syndrome; LTF: lost to follow-up.
1Tauber et al [6]71/FNR20Hard + soft palateYesExcisionCRA4 years
2Ayers et al [7]64/FNRNRHard palateNo---LTF
3Manveen et al [8]40/MNo45Hard palateNoExcisionCRA6 months
4Dunn et al [9]64/FSS, scleroderma, cryoglobulinemia20Hard palate + parotid + nasopharynx + cervical LNNRChemo + RTFourth CRA57 months
5Kolokotronis et al [10]73/FNoNRHard palateNRExcisionRDDOD15 months
6Pijpe et al [11]42/FSS20Hard palate + parotidNRChemo (R)CRA6 months
7Sakuma et al [12]70/FSS17Hard palateYesSpontanous regressionCRA38 months
8Shah et al [13]55/FNR19Hard + soft palateNoExcisionCRA2 years
9Abe et al [14]64/FNo30Hard palateNoExcision---
10Present case61/FNo25Hard palate + parotidYesChemo (R-CHOP)CRA44 months