Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access |
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc |
Journal website http://www.jocmr.org |
Original Article
Volume 2, Number 2, April 2010, pages 62-67
Aortic Stiffness in Prediabetic Adults: Relationship to Insulin Resistance
Figure
Tables
Variable | Control Group N = 45 | Prediabetic adults (Case) N = 113 | P value | ||||
---|---|---|---|---|---|---|---|
All N = 113 | Group A N = 32 | Group B N = 81 | P* | P** | P*** | ||
Group A, prediabetic adult with insulin resistance. Group B, prediabetic adult with insulin sensitive. BMI, body mass index. SBP, systolic blood pressure. DBP, diastolic BP N=number of cases. n.s, non significant. FBS, fasting blood glucose. P*, comparison between group A and control. P**, comparison between group B and control. P***, comparison between all prediabetic adults and control group. | |||||||
Age | 44.4 ± 7.8 | 45.1 ± 6.2 | 44.9 ± 7.1 | 45.3 ± 5.9 | n.s | n.s | n.s |
SBP | 121.1 ± 8.2 | 122.2 ± 9.2 | 120.9 ± 7.9 | 120.1 ± 9.5 | n.s | n.s | n.s |
DBP | 72.9 ± 7.6 | 73.9 ± 6.9 | 74.9 ± 6.5 | 73.5 ± 7.1 | n.s | n.s | n.s |
BMI | 28.6 ± 5.7 | 28.4 ± 5.2 | 28.5 ± 5.2 | 28.4 ± 5.1 | n.s | n.s | n.s |
Waist circumference | 100.3 ± 16.3 | 103 ± 17.2 | 107 ± 11.6 | 102.5 ± 18.2 | n.s | n.s | n.s |
Total lipids | 501.1 ± 42.9 | 491 ± 31.9 | 479 ± 26.7 | 499.7 ± 36.4 | n.s | n.s | n.s |
Triglycerides | 186.8 ± 15.6 | 187.7 ± 12.4 | 187 ± 14.2 | 188.5 ± 11.9 | n.s | n.s | n.s |
FBS | 83.1 ± 7.2 | 114.5 ± 4.8 | 114.8 ± 4.6 | 115.7 ± 4.9 | < 0.01 | < 0.01 | n.s |
HOMA IR | 2.9 ± 0.4 | 3.7 ± 2.5 | 7.5 ± 0.7 | 2.2 ± 0.4 | < 0.01 | n.s | n.s |
Aortic stiffness index | 2.8 ± 1.1 | 5.5 ± 3.1 | 10.2 ± 1.2 | 3.6 ± 0.7 | < 0.001 | n.s | n.s |
Variable | r value | P value |
---|---|---|
Age | 0.81 | < 0.01 |
Total cholesterol | 0.13 | n.s |
Low density lipoprotein | 0.24 | n.s |
Triglyceride | 0.75 | < 0.01 |
HOMA IR | 0.91 | < 0.001 |
Waist circumference | 0.86 | < 0.01 |
Total lipids | 0.4 | n.s |
Systolic blood pressure | 0.33 | n.s |
Diastolic blood pressure | 0.36 | n.s |
High densitylipoprotein | 0.21 | n.s |
Fasting blood glucose | 0.19 | n.s |
Body mass index | 0.16 | n.s |