Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access |
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc |
Journal website http://www.jocmr.org |
Review
Volume 1, Number 5, December 2009, pages 249-261
Computer-aided Image Processing of Angiogenic Histological
Figure
Table
Endothelial marker | Laboratory and clinical qualities |
---|---|
Text partially derived from [2, 38] | |
CD31 | - commonly used |
- cross-reacts with plasma cells | |
- frequent antigen loss occurs due to fixatives containing acetic acid | |
- infiltrates sometimes obscure microvessels, especially single cell sprouts | |
CD34 | - the most reproducible endothelial cell highlighter |
- highlight perivascular stromal cells | |
CD105 | - proliferation-associated and hypoxia-inducible protein |
- preferentially expressed in the activated endothelial cells participating in neoangiogenesis | |
- undetectable or weakly expressed in vessels of normal tissues | |
Tie-2/Tek | - endothelium-specific receptor tyrosine kinase |
- identifies stromal vessels | |
E-9 | - protein specific for activated/proliferating endothelial cells |