Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc
Journal website http://www.jocmr.org

Review

Volume 1, Number 5, December 2009, pages 249-261


Computer-aided Image Processing of Angiogenic Histological

Figure

Figure 1.
Figure 1. Graphical description of ovarian cancer epidemiology (case incidence) in Belarus, 1995, 1999, 2004. Data taken from reference [34].

Table

Table 1. Panendothelial Angiogenesis Markers
 
Endothelial markerLaboratory and clinical qualities
Text partially derived from [2, 38]
CD31- commonly used
- cross-reacts with plasma cells
- frequent antigen loss occurs due to fixatives containing acetic acid
- infiltrates sometimes obscure microvessels, especially single cell sprouts
CD34- the most reproducible endothelial cell highlighter
- highlight perivascular stromal cells
CD105- proliferation-associated and hypoxia-inducible protein
- preferentially expressed in the activated endothelial cells participating in neoangiogenesis
- undetectable or weakly expressed in vessels of normal tissues
Tie-2/Tek- endothelium-specific receptor tyrosine kinase
- identifies stromal vessels
E-9- protein specific for activated/proliferating endothelial cells