Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access |
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc |
Journal website http://www.jocmr.org |
Original Article
Volume 6, Number 6, December 2014, pages 429-434
Treatment of Severe Poison Ivy: A Randomized, Controlled Trial of Long Versus Short Course Oral Prednisone
Figure
Tables
Short course | Long course | Total | |
---|---|---|---|
Male | 7 | 6 | 13 |
Female | 20 | 16 | 36 |
Age mean | 40.89 | 34.09 | 37.88 (SD 17.45, range 15 - 86) |
Enrollment | |||
April | 1 | 3 | 4 |
May | 3 | 3 | 6 |
June | 9 | 5 | 14 |
July | 4 | 3 | 7 |
August | 7 | 2 | 9 |
September | 3 | 6 | 9 |
Short course/27 | Long course/22 | Total/49 | P value | Mean difference | |
---|---|---|---|---|---|
Questionnaire | 18 | 15 | 33 | ||
Telephone | 9 | 7 | 18 | ||
Noncompliance reported | 1 | 2 | 3 | 0.581 | |
Reported improvement of rash | 22 | 21 | 43 | 0.204 | |
Mean time to improvement | 4.42 days (SD 4.13 days) | 2.93 days (SD 1.23 days) | 0.109 | -1.49 days | |
Mean time to resolution | 14.63 days (SD 8.87 days) | 11.7 days (SD 7.39 days) | 0.23 | -2.93 days | |
Rash return?/td> | 4 | 3 | 7 | 0.91 | |
Return in same location?/td> | 4 | 2 | 6 | ||
Side effects | 3 | 0 | 3 | 0.239 | |
Use of other medication: | 15 | 5 | 20 | 0.02 |
Short course/27 | Long course/22 | Total/49 | P value | 95% confidence intervals | |
---|---|---|---|---|---|
Use of other medication: | 15 | 5 | 20 | 0.02 | |
Prednisone, Rx | 9 | 2 | 11 | ||
Depo Medrol, Rx | 1 | 0 | 1 | ||
Triamcinolone, Rx | 1 | 0 | 1 | ||
Calamine, OTC | 2 | 4 | 6 | ||
Antihistamine, OTC | 2 | 2 | 4 | ||
Hydrocortisone cream, OTC | 3 | 0 | 3 | ||
Gold bond lotion, OTC | 1 | 0 | 1 | ||
Other lotion, OTC | 2 | 0 | 2 | ||
Event rate | 22.70% | 55.60% | |||
Absolute risk reduction | 32.90% | 0.139 - 0.385 | |||
Relative risk reduction | 59.20% | 0.331 - 0.611 | |||
Number needed to treat | 3.05 | 2.60 - 7.19 | |||
Relative risk | 0.41 | 0.18 - 0.95 | |||
Odds ratio | 0.24 | 0.067 - 0.824 |