Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc
Journal website http://www.jocmr.org

Original Article

Volume 6, Number 2, April 2014, pages 127-132

Efficacy of Combination Therapy With Sitagliptin and Low-Dose Glimepiride in Japanese Patients With Type 2 Diabetes

Figure

Figure 1.
Figure 1. HbA1c of each patientbefore and after 24 weeks. Left and right panel shows results of high dose and low dose groups, respectively. After 24 weeks of the combination of 1 mg/day glimepiride and 50 mg/day sitagliptin, all subjects except one case in the low dose group exhibit improvement of HbA1c.

Table

Table 1. Patient Background
 
AllHigh dose groupLow dose group
Mean ± SEM, *P < 0.05 vs. Low dose group.
Number (male:female)26 (17:9)11 (6:5)15 (11:4)
Dose of glimepiride4 mg or 5 mg or 6 mg2 mg or 3 mg
Age (year)67.1 ± 1.770.3 ± 2.2*62.8 ± 3.1
Body weight (kg)66.6 ± 2.262.1 ± 2.6*69.6 ± 3.0
HbAlc (%)8.2 ± 0.18.4 ± 0.1*8.1 ± 0.2
Casual plasma glucose (mg/dL)194 ± 10211 ± 21182 ± 8