Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc
Journal website http://www.jocmr.org

Original Article

Volume 6, Number 4, August 2014, pages 245-251


Angiotensin-Converting Enzyme Gene Polymophism in Adult Primary Focal Segmental Glomerulosclerosis

Tables

Table 1. Demographics of the II Group Versus ID/DD Group at Diagnosis
 
IIa (n = 23)ID/DDa (n = 22)P valueb
aMedian (interquartile range). bMann-Whitney U test (P < 0.05 is statistically significant). MAP: mean arterial pressure; BMI: body mass index.
Age (years)27 (21 - 46)33 (22 - 53)0.46
Gender (M:F)17:0613:09
Race (M:C:I:O)14:7:1:114:8:0:0
Systolic BP (mm Hg)134 (124 - 148)132 (126 - 150)0.31
Diastolic BP (mm Hg)78 (74 - 85)84 (74 - 92)0.24
MAP (mm Hg)99 (90 - 105)103 (91 - 109)0.18
Weight (kg)65.2 (56.8 - 75.4)67.8 (58 - 73)0.69
BMI (kg/m2)24.4 (21.3 - 29.2)25.2 (22.5 - 27.8)0.69
Serum albumin (g/dL)22 (16 - 32)26 (17 - 39)0.51
Total cholesterol (mmol/L)7.62 (6.01 - 9.65)7.48 (5.8 - 12.2)0.94
TG (mmol/L)1.84 (1.28 - 2.53)2.91 (2.26 - 4.29)0.69
LDL (mmol/L)4.61 (3.35 - 6.02)4.69 (3.05 - 8.70)0.90
eGFR (mL/min/1.73 m2)88 (50 - 139)63 (45 - 122)0.57
uPCI (g/mmol) (NR < 0.02)0.56 (0.37 - 0.88)0.42 (0.17 - 0.81)0.21

 

Table 2. Demographics of the Two Study Group at Study Recruitment
 
IIa (n = 23)ID/DDa (n = 22)P valueb
aMedian (interquartile range). bMann-Whitney U.
Age (years)31 (23 - 48)38 (27 - 54)0.57
Gender (M:F)17:0613:09
Race (M:C:I:O)14:7:1:114:8:0:0
Systolic BP (mm Hg)126 (122 - 120)127 (117 - 138)0.56
Diastolic BP (mm Hg)74 (68 - 81)80 (67 - 83)0.53
MAP (mm Hg)93 (86 - 100)93 (85 - 99)0.97
Weight (kg)68.0 (52.8 - 75.3)66.4 (59 - 77)0.76
BMI (kg/m2)25.3 (21.3 - 29.5)25.8 (20.5 - 30.1)0.66
Serum albumin (g/dL)46 (41 - 47)43 (40 - 45)0.17
Total cholesterol (mmol/L)5.39 (5.16 - 5.99)5.59 (4.63 - 6.83)0.89
TG (mmol/L)1.43 (0.88 - 2.17)1.74 (1.02 - 3.02)0.38
LDL (mmol/L)3.38 (2.34 - 3.90)2.91 (2.26 - 4.29)0.82
Creatinine (μmol/L)80 (64 - 113)100 (70 - 147)0.10
eGFR (mL/min/1.73 m2)91 (58 - 127)62 (42 - 98)0.06
uPCI (g/mmol)0.02 (0.01 - 0.04)0.04 (0.02 - 0.14)0.03
Duration of follow-up (years)3.3 (1.5 - 5.8)4.0 (2.3 - 5.7)