Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc
Journal website http://www.jocmr.org

Original Article

Volume 4, Number 5, October 2012, pages 318-322

Restless Legs Syndrome in Multiple Myeloma Patients

Tables

Table 1. Demographic Properties of the MM Patients and Healthy Control Subjects
 
Patients included in the study (n = 62)Healthy Controls (n = 62)
Age (year)56.6 ± 19.3 (36 - 78)56.3 ± 18.7 (35 - 76)
GenderMale (n) = 38; Female (n) = 24Male (n) = 37; Female (n) = 25
Body Mass Index (BMI)23.4 ± 6.323.2 ± 6.5
ISS (International Staging System) stageStage I (n) = 6; Stage II (n) = 25;
Stage III (n) = 28; Unknown (n) = 3		-
Myeloma typeIgG (n) = 34; IgA (n) = 18; Light chain (n) = 10-
Presence of lytic lesionn = 41-

 

Table 2. Restless Legs Syndrome (RLS) Frequency and IRLSSG-RS (International RLS Study Group-Rating Scale) and ESS (Epworth Sleepiness Scale) Scores in MM Patients and Healthy Control Subjects
 
MM patients (n = 62)Healthy Controls (n = 62)P value
Data presented number (%) of patients or mean ± SD. aChi-Square test; bStudent’s t-test and Mann-Whitney U-test; NS, not statistically significant (P > 0.05).
RLS diagnosis (n)11 (17.74%)2 (3.23%)< 0.01a
ESS score6.65 ± 4.396.69 ± 4.26NSb
IRLSSG-RS Score21.23 ± 6.4320.98 ± 6.35NSb

 

Table 3. Comparison of HADS (Hospital Anxiety and Depression Scale) Scores and SF-36 Subscales Between MM Patients With and Without RLS
 
MM (RLS +)MM (RLS -)P value
HADS Depression9.1 ± 4.56.7 ± 4.0< 0.01
HADS Anxiety9.2 ± 4.26.6 ± 4.2< 0.01
SF-36 Physical Functioning (PF)42.07 ± 11.5644.56 ± 11.34< 0.01
SF-36 Role-Physical (RP)45.02 ± 7.9645.82 ± 10.57NS
SF-36 Body Pain (BP)49.78 ± 8.7149.22 ± 8.96NS
SF-36 General Health (GH)48.28 ± 8.1948.42 ± 9.32NS
SF-36 Vitality (VT)55.23 ± 9.5755.43 ± 9.75NS
SF-36 Social Functioning (SF)44.05 ± 10.1444.02 ± 9.98NS
SF-36 Role-Emotional (RE)41.83 ± 11.6544.69 ± 11.34< 0.01
SF-36 Mental Health (MH)45.59 ± 10.7748.28 ± 10.89< 0.01