| Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc |
| Journal website http://www.jocmr.org |
Original Article
Volume 4, Number 5, October 2012, pages 309-313
Pleiotropic Effects of Sitagliptin in the Treatment of Type 2 Diabetes Mellitus Patients
Tables
| ΔCr | ΔUA | ||
|---|---|---|---|
| Correlations among blood pressure, creatinine, and uric acid levels; correlation between changes in ALP and HbA1c. | |||
| ΔSBP | r | -0.236 | -0.134 |
| P | < 0.01 | < 0.05 | |
| ΔDBP | r | -0.161 | -0.079 |
| P | < 0.01 | NS | |
| ΔCr | r | 0.342 | |
| P | < 0.01 | ||
| ΔHbA1c | |||
| ΔALP | r | 0.383 | |
| P | < 0.01 | ||
| 0 weeks | 4 weeks | 12 weeks | |
|---|---|---|---|
| ANOVA: vs. baseline ** P < 0.01 * P < 0.05vs. 4 weeks †† P < 0.01. | |||
| HbA1c (%) | 8.02 ± 1.12 | 7.71 ± 0.98 ** | 7.38 ± 0.89 **,†† |
| SBP (mmHg) | 128.8 ± 14.3 | 127.6 ± 13.7* | 127.4 ± 13.4** |
| DBP (mmHg) | 74.7 ± 9.8 | 74.0 ± 9.6 | 74.0 ± 9.3* |
| TCHOL | 198.2 ± 34.3 | 192.6 ± 34.3** | 191.7 ± 32.5** |
| HDL (mg/dL) | 57.1 ± 15.2 | 56.4 ± 14.9 | 56.2 ± 14.8 |
| ppTGs (mg/dL) | 157.4 ± 99.4 | 144.9 ± 87.2* | 146.3 ± 86.8* |
| fTGs (mg/dL) | 132.4 ± 141.2 | 125.0 ± 107.4 | 136.9 ± 125.2 |
| Cr (mg/dL) | 0.75 ± 0.22 | 0.77 ± 0.23** | 0.78 ± 0.24** |
| UA (mg/dL) | 5.07 ± 1.21 | 5.28 ± 1.32** | 5.40 ± 1.45** |
| ALP (IU/L) | 255.3 ± 93.0 | 240.3 ± 86.1** | 231.8 ± 78.2** |
| GOT (IU/L) | 25.3 ± 15.9 | 25.5 ± 18.6 | 25.3 ± 18.0 |
| GPT (IU/L) | 27.7 ± 21.2 | 26.3 ± 21.7 | 26.9 ± 22.8 |
| γGTP (IU/L) | 45.7 ± 50.4 | 44.1 ± 55.3 | 44.8 ± 54.9 |
| LDH (IU/L) | 244.6 ± 63.2 | 249 ± 60.2 | 246 ± 52.6 |