Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc
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Case Report

Volume 8, Number 4, April 2016, pages 346-350


Focal Epithelial Hyperplasia (Heck’s Disease) in a 57-Year-Old Brazilian Patient: A Case Report and Literature Review

Figures

Figure 1.
Figure 1. Multiple papules and nodules, sessile, coalescent, normal in colour, located on the upper lip mucosa and causing double lip appearance (A). Solitary tongue nodule, sessile, measuring approximately 20 mm on its largest diameter, with smooth and lobulated surface, similar in colour to the surrounding mucosa (B).
Figure 2.
Figure 2. Immediate postoperative aspect (A) and surgical specimen (B).
Figure 3.
Figure 3. H&E-stained photomicrographs displaying characteristic features of FEH. Low-power magnification shows pseudocarcinomatous hyperplasia, marked acanthosis and elongated rete ridges (A, × 40; B, × 100). Spinous layer with parakeratosis, anisokaryosis and typical koilocytosis (C, × 200). High magnification allows clearer depiction of koilocytosis showing keratinocytes with pyknotic nuclei, surrounded by clears areas (D, × 400, arrow).
Figure 4.
Figure 4. Clinical view, with no signs of recurrence after 36-month follow-up. Lateral view (A) and superior view (B).