| Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc |
| Journal website http://www.jocmr.org |
Original Article
Volume 8, Number 3, March 2016, pages 220-224
Effects of Obstructive Sleep Apnea Hypopnea Syndrome on Blood Pressure and C-Reactive Protein in Male Hypertension Patients
Tables
| Item | Normal control group (n = 35) | Mild OSAHS group (n = 28) | Moderate OSAHS group (n = 57) | Severe OSAHS group (n = 68) |
|---|---|---|---|---|
| Compared with the normal control group, *P < 0.05 and †P < 0.01. | ||||
| Age (year) | 43 ± 9 | 41 ± 12 | 45 ± 8 | 45 ± 7 |
| BMI (kg/m2) | 25.62 ± 2.79 | 26.07 ± 4.11 | 26.80 ± 2.54* | 27.15 ± 2.20* |
| FBG (mmol/L) | 5.07 ± 1.61 | 5.29 ± 1.78 | 5.54 ± 1.43 | 5.47 ± 1.26 |
| TG (mmol/L) | 1.82 ± 1.80 | 2.74 ± 2.02 | 2.98 ± 1.97† | 2.94 ± 1.79† |
| LDL-C (mmol/L) | 2.88 ± 1.35 | 3.15 ± 1.69 | 3.07 ± 1.41 | 3.21 ± 1.32 |
| HDL-C (mmol/L) | 1.14 ± 0.47 | 1.06 ± 0.81 | 0.98 ± 0.35 | 0.92 ± 0.29 |
| hs-CRP (mg/L) | 2.33 ± 2.82 | 3.68 ± 6.56 | 5.71 ± 8.17* | 6.45 ± 7.25† |
| Group | Case number | dSBP (mm Hg) | dDBP (mm Hg) | nSBP (mm Hg) | nDBP (mm Hg) | Nocturnal blood pressure reduction percentage (%) |
|---|---|---|---|---|---|---|
| Compared with the normal control group, *P < 0.01; compared with the mild OSAHS group, †P < 0.05 and ‡P < 0.01. | ||||||
| Normal control group | 35 | 137.3 ± 14.6 | 88.1 ± 10.4 | 117.9 ± 11.2 | 77.4 ± 8.5 | 13.5 ± 5.4 |
| Mild OSAHS group | 28 | 135.4 ± 18.2 | 89.2 ± 12.1 | 119.1 ± 12.3 | 82.0 ± 11.4 | 11.8 ± 8.6 |
| Moderate OSAH group | 57 | 136.8 ± 13.9 | 90.4 ± 9.7 | 128.6 ± 17.1*,‡ | 86.7 ± 19.3*,† | 5.8 ± 4.2*,‡ |
| Severe OSAHS group | 68 | 138.6 ± 11.5 | 91.7 ± 11.2 | 134.3 ± 16.4*,‡ | 90.3 ± 17.1*,‡ | 2.9 ± 2.1*,‡ |
| Dependent variable | Independent variable | Adjusted R2 | P* | B | P† |
|---|---|---|---|---|---|
| *P value of the adjusted R2; †P value of B. | |||||
| nSBP | AHI | 0.34 | < 0.01 | 1.72 | < 0.01 |
| hs-CPR | 0.12 | < 0.01 | 0.88 | < 0.01 | |
| nDBP | AHI | 0.29 | < 0.01 | 1.64 | < 0.01 |
| hs-CRP | 0.09 | < 0.01 | 0.83 | < 0.01 | |
| Nocturnal blood pressure reduction percentage | AHI | 0.30 | < 0.01 | -0.11 | < 0.01 |
| hs-CRP | 0.18 | < 0.01 | -0.35 | < 0.01 | |