Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc
Journal website http://www.jocmr.org

Case Report

Volume 7, Number 12, December 2015, pages 1007-1012

Primary Diffuse Large B-Cell Lymphoma of Central Nervous System: Is Still Surgery an Unorthodox Treatment?

Figures

Figure 1.
Figure 1. Pre-operative brain MRI T1 sequence.
Figure 2.
Figure 2. Pre-operative brain MRI FLAIR sequence which shows the peritumoral edema.
Figure 3.
Figure 3. Pre-operative brain MRI T1 sequence with contrast gadolinium which shows the enhancing of the tumor.
Figure 4.
Figure 4. Post-operative brain MRI SPGR imaging which confirms the removal of the tumor.
Figure 5.
Figure 5. (a) Histology shows perivascular spread of highly anaplastic lymphoid cells with numerous mitotic figures (hematoxylin and eosin stain, original magnification × 40). (b) The tumor cells express the pan-B-cell marker CD20 (immunohistochemistry, original magnification × 40). (c) The malignant cells invade the parenchyma which demonstrates glial fibrillary-acid protein (GFAP) immunoreactivity (immunohistochemistry, original 15 magnification × 20).