Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc
Journal website http://www.jocmr.org

Original Article

Volume 7, Number 10, October 2015, pages 802-806

Visit-to-Visit Variability and Seasonal Variation in Blood Pressure With Single-Pill Fixed-Dose Combinations of Angiotensin II Receptor Blocker/Calcium Channel Blocker and Angiotensin II Receptor Blocker/Diuretic in Hypertensive Patients

Figures

Figure 1.
Figure 1. Time courses of blood pressure (BP) (A) and pulse rate (PR) (B) in each month for 12 months in the ARB/CCB and ARB/DI groups. *P < 0.05 vs. ARB/DI group. NS: not significant.
Figure 2.
Figure 2. Time courses of systolic and diastolic blood pressure (SBP and DBP) (A) and pulse rate (PR) (B) in each season for 12 months. *P < 0.05 vs. ARB/DI group. NS: not significant.
Figure 3.
Figure 3. Visit-to-visit variabilities of systolic blood pressure (SBP) (A), diastolic BP (DBP) (B) and pulse rate (PR) (C). NS: not significant.
Figure 4.
Figure 4. Seasonal variations of systolic blood pressure (SBP) (A), diastolic BP (DBP) (B) and pulse rate (PR) (C). NS: not significant.

Table

Table 1. Baseline Characteristics in the ARB/CCB and ARB/DI Groups
 
ARB/CCB (n = 30)ARB/DI (n = 17)
Continuous variables are expressed as mean ± SD. ARB: angiotensin II receptor blocker; CCB: calcium channel blocker; DI: diuretic; BMI: body mass index; DM: diabetes mellitus; DL: dyslipidemia; CAD: coronary artery disease. %CCB in the ARB/CCB group and %DI in the ARB/DI group indicate the percentages of CCB except for amlodipine and DI except for hydrochlorothiazide, respectively. *P < 0.05 vs. ARB/CCB.
Age, years70 ± 1068 ± 10
Male, %6059
BMI, kg/m225 ± 324 ± 3
DM, %136
DL, %5776
CAD, %1747*
Medications
  CCB, %759*
  DI, %130
  αβ blocker, %712
  β blocker, %1724
  Aldosterone antagonist, %712