Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access |
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc |
Journal website http://www.jocmr.org |
Short Communication
Volume 7, Number 4, April 2015, pages 257-261
Inflammatory Bowel Disease as a Risk Factor for Premature Coronary Artery Disease
Table
Study | Patient population | Result |
---|---|---|
Dagli et al [5] | IBD: 40 Healthy patients: 40 | IBD patients had a significant increase in carotid intimal media thickness (cIMT) compared to the control group (P = 0.01) |
Dorn et al [6] | CD: 4,532 UC: 9,533 | SMR = 0.7 - 1.5 (NS) SMR = 0.5 - 1.1 (NS) |
Kristensen et al [7] | CD: 4,732 UC: 13,622 | Relative risk of myocardial infarction = 1.49 (CI: 1.16 - 1.93) in patients with an active flare and 2.05 (CI: 1.58 - 2.65) in chronic disease state |
Yarur et al [8] | CD: 173 UC: 183 | Adjusted hazard ratio for developing CAD in IBD group = 4.08 (95% CI: 2.49 - 6.70) |
Papa et al [9] | IBD: 52 Healthy patients: 20 | cIMT significantly higher in IBD patients (0.63 ± 0.15 mm) compared with controls (0.53 ± 0.08 mm) (P = 0.008) |
Ruisi et al (current study) | IBD: 300 | SMR = 0.0 (NS) 99.7% of the study patients did not have any reported CV events over the 2-year follow-up period |