J Clin Med Res

Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access

Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc

Journal website http://www.jocmr.org

Original Article

Volume 7, Number 4, April 2015, pages 242-247

Protective Effects of Phosphocreatine Administered Post-Treatment Combined With Ischemic Post-Conditioning on Rat Hearts With Myocardial Ischemia/Reperfusion Injury

Figure

Figure 1. Results of western blot detection of left ventricular anterior ischemic myocardium p-Akt and Bcl-2 protein expression. The corresponding densitometric analysis is shown as a bar chart. *P < 0.05 vs. I/R group; ▲P < 0.05 vs. IPost group and PCr group.

Tables

**Table 1.** Comparison of Serum CK, LDH, and MPO in Each Experimental Group (x ± s, n = 10).
Group	CK (U/L)	LDH (× 10³ U/L)	MPO (U/L)
*P < 0.05 vs. I/R group; †P < 0.05 vs. IPost group and PCr group.
I/R	16.42 ± 2.74	5.21 ± 0.34	73.16 ± 8.41
IPost	8.74 ± 1.19*	2.90 ± 0.14*	37.48 ± 6.36*
PCr	9.04 ± 1.42*	2.80 ± 0.12*	36.65 ± 3.71*
PCr + IPost	5.79 ± 1.34*†	1.85 ± 0.15*†	19.92 ± 4.16*†

**Table 2.** Percentages of Risk Area and Infarct Size (x ± s, n = 7)
Group	BW (g)	LV (g)	AAR/LV (%)	IS (%)
*P < 0.05 vs. I/R group; †P < 0.05 vs. IPost group and PCr group. BW: body weight; LV: left ventricle.
I/R	278.24 ± 3.34	0.79 ± 0.02	36.74 ± 5.13	51.04 ± 3.88
IPost	280.83 ± 11.12	0.80 ± 0.05	35.62 ± 3.22	38.27 ± 2.67*
PCr	279.48 ± 6.79	0.79 ± 0.06	35.40 ± 4.18	35.78 ± 3.57*
PCr + IPost	275.20 ± 8.56	0.78 ± 0.03	24.85 ± 3.10*†	18.52 ± 1.33*†

**Table 3.** Comparison of Serum NF-κB and TNF-α (x ± s, n = 7)
Group	NF-κB (ng/mL)	TNF-α (pg/mL)
*P < 0.05 vs. I/R group; †P < 0.05 vs. IPost group and PCr group.
I/R	67.98 ± 8.22	34.95 ± 5.12
IPost	40.92 ± 4.47*	17.46 ± 1.97*
PCr	16.81 ± 2.17*	39.74 ± 2.77*
PCr + IPost	26.23 ± 2.68*†	10.83 ± 1.63*†