| Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc |
| Journal website http://www.jocmr.org |
Original Article
Volume 7, Number 1, January 2015, pages 33-36
Clinical Markers of Crohn’s Disease Severity and Their Association With Opiate Use
Tables
| Opiate users (n = 50) | Non-opiate users (n = 58) | P-value | |
|---|---|---|---|
| Age | 48.46 ± 15.99 | 52.28 ± 18.96 | 0.265 |
| Gender (males) | 30 (60.00%) | 37 (63.79%) | 0.686 |
| Age of diagnosis | 29.41 ± 15.68 | 33.42 ± 16.78 | 0.213 |
| Disease duration (years) | 14.5 (12.0, 24.0) | 15.0 (10.0, 21.0) | 0.769 |
| Opiate users (n = 50) | Non-opiate users (n = 58) | P-value | |
|---|---|---|---|
| SIBDQ | 3.80 ± 1.21 | 4.34 ± 1.35 | 0.036 |
| IBS diagnosis | 10 (20.00%) | 8 (13.79%) | 0.388 |
| History of fistula | 20 (40.00%) | 13 (22.41%) | 0.048 |
| Enterocutaneous | 4 (8.00%) | 4 (6.90%) | 1.000 |
| Enteroenteric | 11 (22.00%) | 4 (6.90%) | 0.024 |
| Entervesicular | 1 (2.00%) | 0 (0.00%) | 0.463 |
| Rectovaginal | 1 (2.00%) | 3 (5.17%) | 0.622 |
| Perianal | 9 (18.00%) | 12 (20.69%) | 0.725 |
| Any surgical history | 33 (66.00%) | 36 (62.07%) | 0.672 |
| History of abscess drain | 12 (24.00%) | 15 (25.86%) | 0.824 |
| History of bowel resection | 27 (54.00%) | 21 (36.21%) | 0.064 |
| Ostomy | 9 (18.00%) | 12 (20.69%) | 0.725 |
| Stricture | 8 (16.00%) | 10 (17.24%) | 0.863 |
| Tobacco | |||
| Current | 11 (22.00%) | 2 (3.45%) | 0.010 |
| Past | 18 (36.00%) | 22 (37.93%) | |
| Never | 21(42.00%) | 34 (58.62%) | |
| Past cocaine | 1 (2.00%) | 1 (1.72%) | 1.000 |
| Past marijuana | 6 (12.00%) | 7 (12.07%) | 0.991 |
| Alcohol | |||
| Daily | 3 (5.26%) | 2 (4.00%) | 0.479 |
| Weekly | 10 (17.54%) | 8 (16.00%) | |
| Monthly | 10 (17.54%) | 9 (18.00%) | |
| Few times/year | 24 (42.11%) | 15 (30.00%) | |
| Never | 10 (17.54%) | 16 (32.00%) |