Effect of Diet on Serum Creatinine in Healthy Subjects During a Phase I Study

Abstract

Creatinine is widely used as an indirect marker of renal function. However, interfering factors such as diet, exercise and problems with the assay can generate false results and misinterpretation of real kidney function. In this article, we report the dietary effects on serum creatinine during a phase I single dose escalation study and discuss the reasons why serum creatinine should be measured under fasting conditions.




J Clin Med Res. 2016;8(11):836-839
doi: http://dx.doi.org/10.14740/jocmr2738w